Authors’ Response: High Levels of Intrauterine Corticotrophin-Releasing Hormone, Urocortin, Tryptase, and Interleukin-8 in Spontaneous Abortions
نویسندگان
چکیده
منابع مشابه
High levels of intrauterine corticotropin-releasing hormone, urocortin, tryptase, and interleukin-8 in spontaneous abortions.
Stress induces CRH secretion that activates hypothalamic-pituitary-adrenal axis and is also abortogenic. In addition to hypothalamus, CRH and its analog urocortin (Ucn) are also secreted locally outside the brain where they activate mast cells leading to inflammation; however, the level of CRH and Ucn or mast cell mediators has not been examined in products of conception (POC). CRH and Ucn were...
متن کاملMaternal plasma corticotrophin-releasing factor and urocortin levels in post-term pregnancies.
OBJECTIVE Corticotrophin-releasing factor (CRF) and urocortin are two placental neuropeptides that are involved in the mechanisms of labour by modulating myometrial activity. Maternal plasma levels of both CRF and urocortin are increased at term and preterm labour, whilst those of CRF are reduced in women who are destined to experience post-term delivery. The present study evaluated maternal pl...
متن کاملModulation of free corticotrophin-releasing hormone, adrenal and placental steroid hormone levels induced by mifepristone during pregnancy.
UNLABELLED Mifepristone is a progesterone receptor antagonist widely used in obstetrics. The aim of the study was to focus on free corticotrophin-releasing hormone (CRH) and also describe modulation of adrenal and placental steroid hormone concentrations induced by mifepristone. METHODS Twenty-six women were enrolled in the study. They received mifepristone for termination of pregnancy. Mater...
متن کاملCorrelation of Copper and Zinc in Spontaneous Abortions
Objective Trace metals are required in minute amounts for normal human growth and physiological function of the body and might play a vital role in the pregnancy and outcome. The study was conducted to assess the role of trace metals zinc (Zn) and copper (Cu) among women with history of spontaneous abortion (SAb Cases) with respect to women without such history (Controls). MaterialsAndMethods A...
متن کاملEffects of cold stress on the messenger ribonucleic acid levels of corticotrophin-releasing hormone and thyrotropin-releasing hormone in hypothalami of broilers.
In this study, seventy 1-d-old male broiler chicks were randomly allocated to 10 groups to investigate the effect of cold stress on the messenger RNA (mRNA) levels of corticotrophin-releasing hormone (CRH) and thyrotropin-releasing hormone (TRH) in hypothalami. The chicks were maintained at 30 +/- 2 degrees C temperature and given free access to standard chow and water. Until 15 d old, the 6 tr...
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ژورنال
عنوان ژورنال: The Journal of Clinical Endocrinology & Metabolism
سال: 2003
ISSN: 0021-972X,1945-7197
DOI: 10.1210/jc.2003-031382